More than 50 percent of cancer patients are cured, largely due to laboratory and clinical research leading to the discovery of new cancer treatments.
Research trials give patients access to new anti-cancer therapies often long before they are available elsewhere.
Marshfield Clinic Research Institute offers numerous cancer clinical trials to our adult and pediatric patients, including:
- New drug therapies
- Autologous bone marrow transplantation
- Genetic advancements
- Cancer control studies
Marshfield Clinic is an active partner with leading national research centers such as the:
- National Cancer Institute funded CCOP – linking community physicians with National Cancer Institute clinical research programs.
- Eastern Cooperative Oncology Group (ECOG)
- National Surgical Adjuvant Breast and Bowel Program (NSABP)
- Children’s Oncology Group (COG)
- University of Rochester Cancer Center
- M. D. Anderson Cancer Center
- South West Oncology Group (SWOG)
- Gynecological Oncology Group (GOG)
- Cancer Trials Support Unit (CTSU)
Marshfield Clinic physicians also participate in pharmaceutical sponsored studies and develop their own research studies within the Marshfield Clinic system. We also conduct symptom control, quality of life and prevention studies.
Types of Cancer Research
Clinical Trial: A study (or protocol) conducted with cancer patient volunteers to evaluate a new treatment, such as drugs, surgery or radiation therapy. Each study is designed to answer scientific questions and to find new and better ways to help cancer patients. Clinical trials are carried out in phases. Each new phase of a clinical trial depends on and builds on information from an earlier phase. Patients may be eligible for studies in different phases depending on their general condition and the type and stage of their cancer.
Phase 1 Studies - A new research treatment is given to a small number of patients. The researchers must find the best way to give a new treatment and how much of it can be given safely. Phase 1 studies may involve significant risks and are offered only to patients whose cancer has spread and who would not be helped by other known treatments.
Phase 2 Studies - Determine the effect of a research treatment on various types of cancer.
Phase 3 Studies – Compares treatment with the standard treatment to see which is more effective.
Phase 4 Studies - The new treatment may be tested by combining it with other effective treatments to discover if the combined treatment is more effective.
Treatment Trial: Evaluates promising new treatments for safety and effectiveness. The treatment methods being evaluated may be surgery, drugs, radiation techniques, or a combination of treatments.
Cancer Control Trial: Studies that evaluate and possibly manage the side effects of cancer or its treatment. These include pain management, fatigue, the psychological impact of the disease and ways to improve comfort and quality of life.
Chemoprevention Trial: Studies that usually involve people who may be at risk of developing cancer. These studies aim to prevent cancer in people with medical conditions that may lead to cancer, or to prevent a second cancer in people successfully treated for a previous cancer.
Screening Trials: Used to identify people without symptoms, who have risk factors for cancer. These studies may detect hidden disease and permit early treatment. Persons with familial conditions may also be directed to genetic counseling when appropriate.