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FOR IMMEDIATE RELEASE

Marshfield Clinic researchers are seeking volunteers with Type 2 diabetes for a research study that will look at the effectiveness and safety of an investigational diabetes medication combination.

Steven Yale, M.D., a Marshfield Clinic Internal Medicine physician, is the principal investigator for this study at Marshfield Clinic Marshfield Center and Anshu Varma, M.D., a Marshfield Clinic Internal Medicine physician, is the principal investigator at Marshfield Clinic Weston Center.

The purpose of the study is to examine the safety and efficacy of a medication combination of metformin and pioglitazone, medications already approved for Type 2 diabetes treatment, along with either sitagliptin or a placebo over a 26-week treatment period, to see if adding sitagliptin provides Type 2 diabetes patients with better glycemic control.

Participants in the randomized, double-blind study will receive a combination of metformin and pioglitazone along with either sitagliptin or a placebo. They will receive study-related care and medication at no charge.

Adults age 18 – 78 who have an HbA1c levels between 7.5 mg/dl and 11 mg/dl, and who are currently taking combination treatment, with one of the treatments being metformin, may be eligible to participate.

Merck & Co., Inc., of Whitehouse Station, New Jersey, is the study’s sponsor.

For more information, or to see if you qualify to participate in the study, contact Paula Mueller, Clinical Research coordinator at Marshfield Clinic Weston Center, at 715-393-1335, or Katie Moore, Clinical Research coordinator at Marshfield Clinic Marshfield Center, at 715-389-3632.

The Marshfield Clinic system provides patient care, research and education with 45 locations in northern, central and western Wisconsin, making it one of the largest comprehensive medical systems in the United States.